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What Is 4F-PHP?

4F-PHP (also known as 4F-MPH) is a novel research chemical belonging to the stimulant class. Its IUPAC name is methyl 2-(4-fluorophenyl)-2-(piperidin-2-yl)acetate, with a chemical formula of C₁₄H₁₈FNO₂ and a molecular weight of 251.30.

This compound is relatively new in the research chemical market, so most available data comes from studies on its analog, 4-MPH. Research conducted by institutions such as the US Environmental Protection Agency (EPA), ACD/Labs, and ChemAxon provides valuable insights into its properties.

Key Research Findings on 4-MPH (Analog of 4F-PHP)

• Boiling Point: 281.69 °C
• Melting Point: 67.79 °C
• Vapor Pressure: 0.00203
• Water Solubility (25°C): 30,730 mg/L
• Wastewater Treatment Removal:
  • Complete removal: 1.97%
  • Biodegradation: 0.09%
  • Sludge adsorption: 1.88%
  • Air release: 0.00%

Additional research by ACD/Labs revealed:

• 2 hydrogen bond acceptors
• 1 hydrogen bond donor
• 1 freely rotating bond
• Refractive index: 1.503
• Surface tension: 34.4 ± 3.0 dyne/cm
• Flash point: 1112.7 ± 12.6 °C
• Boiling point at 760 mmHg: 285.2 ± 25.0 °C

ChemAxon’s topology report further details:

• 28 atom count
• 29 bond count
• 2 cyclomatic numbers
• 1 chain atom count
• 2 chain bond count
• 2 asymmetric atom counts
• 1 rotatable bond count

Other studies indicate:

• 13 heavy atom count
• 21.3 Ų topological polar surface area
• 1 covalently bonded unit count
• 2 undefined atom stereocenter counts

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Important Disclaimer

4F-PHP and its analogs (such as 4-MPH) are strictly for forensic and scientific research purposes only. These chemicals are not intended for human or animal consumption and should only be handled by qualified professionals in controlled laboratory environments.

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